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1

Maternal mortality in sub-Saharan Africa: the contribution of ineffective blood transfusion services

I Bates, GK Chapotera, S McKew, N Van Den Broek

Journal:

BJOG: An International Journal of Obstetrics & Gynaecology

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

2

Differences between aerobic and anaerobic degradation of microphytobenthic biofilm-derived organic matter within intertidal sediments

McKew, Boyd A., Dumbrell, Alex J., Taylor, Joe D., McGenity, Terry J., Underwood, Graham J.C.

Journal:

FEMS Microbiology Ecology

Year:

2013

Language:

english

File:

PDF, 322 KB

english, 2013

3

Phenotypic screens as a renewed approach for drug discovery

Zheng, Wei, Thorne, Natasha, McKew, John C.

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 311 KB

english, 2013

4

Hunter's Tropical Medicine and Emerging Infectious Disease || Hematologic Diseases

Year:

2013

Language:

english

File:

PDF, 2.30 MB

english, 2013

5

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Kouznetsova, Jennifer, Sun, Wei, Martínez-Romero, Carles, Tawa, Gregory, Shinn, Paul, Chen, Catherine Z, Schimmer, Aaron, Sanderson, Philip, McKew, John C, Zheng, Wei, García-Sastre, Adolfo

Journal:

Emerging Microbes & Infections

Year:

2014

Language:

english

File:

PDF, 1.59 MB

english, 2014

6

Importance and controls of anaerobic ammonium oxidation influenced by riverbed geology

Lansdown, K., McKew, B. A., Whitby, C., Heppell, C. M., Dumbrell, A. J., Binley, A., Olde, L., Trimmer, M.

Journal:

Nature Geoscience

Year:

2016

Language:

english

File:

PDF, 570 KB

english, 2016

7

ChemInform Abstract: Preparation of 4,5-Disubstituted Pyrimidines: Ring Substitution of 5-Mesyloxymethylpyrimidines.

Howard Sard, Mario D. Gonzalez, Anu Mahadevan, John McKew

Journal:

Year:

2001

File:

PDF, 28 KB

2001

8

A General Method for C3 Reductive Alkylation of Indoles.

Anu Mahadevan, Howard Sard, Mario Gonzalez, John C. McKew

Journal:

Year:

2003

File:

PDF, 135 KB

2003

9

Thermodynamic characterization of cytosolic phospholipase A2 alpha inhibitors

Manjunath K. Ramarao, Marina W.H. Shen, Elizabeth A. Murphy, Weili Duan, Yajuan Zhao, John McKew, Katherine L. Lee, Paresh Thakker, Mark L. Behnke, James D. Clark

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 564 KB

english, 2008

10

β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action

Jason Xiang, Manus Ipek, Vipin Suri, May Tam, Yuzhe Xing, Nelson Huang, Yanling Zhang, James Tobin, Tarek S. Mansour, John McKew

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

11

Structure–activity relationships of indole cytosolic phospholipase A2α inhibitors: substrate mimetics

John C McKew, Frank Lovering, James D Clark, Jean Bemis, YiBin Xiang, Marina Shen, Wen Zhang, Juan C Alvarez, Diane Joseph-McCarthy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 260 KB

english, 2003

12

1,2,4-Oxadiazolidin-3,5-diones and 1,3,5-triazin-2,4,6-triones as cytosolic phospholipase A2α inhibitors

Ariamala Gopalsamy, Hui Yang, John W. Ellingboe, John C. McKew, Steve Tam, Diane Joseph-McCarthy, Wen Zhang, Marina Shen, James D. Clark

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 181 KB

english, 2006

13

Regioselectivity in the iodolactonization of 1,6-heptadien-4-carboxylic acid derivatives

Mark J. Kurth, Edward G. Brown, Eric J. Lewis, John C. McKew

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 269 KB

english, 1988

14

A general method for C3 reductive alkylation of indoles

Anu Mahadevan, Howard Sard, Mario Gonzalez, John C. McKew

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

15

Functional morphology of the compass-rotular ligament ofEchinus esculentus(Echinodermata: Echinoida): a non-mutable collagenous component of Aristotle’s lantern

Iain C. Wilkie, Mary McKew, M. Daniela Candia Carnevali

Journal:

Year:

2005

Language:

english

File:

PDF, 2.22 MB

english, 2005

16

Benzhydrylquinazolinediones: Novel cytosolic phospholipase A2α inhibitors with improved physicochemical properties

Steven J. Kirincich, Jason Xiang, Neal Green, Steve Tam, Hui Y. Yang, Jaechul Shim, Marina W.H. Shen, James D. Clark, John C. McKew

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.91 MB

english, 2009

17

The development of sarcoidosis with the use of alemtuzumab – clues to T-cell immune reconstitution

Jecko Thachil, Vittal Jadhav, Manish Gautam, Steve Mckew, Arvind Arumainathan, Daniel Collins, Colin Smyth, Janice Harper, Andrew Pettitt

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 51 KB

english, 2007

18

Effects of temperature and biostimulation on oil-degrading microbial communities in temperate estuarine waters

Frédéric Coulon, Boyd A. McKew, A. Mark Osborn, Terry J. McGenity, Kenneth N. Timmis

Journal:

Environmental Microbiology

Year:

2007

Language:

english

File:

PDF, 328 KB

english, 2007

19

Determining the identity and roles of oil-metabolizing marine bacteria from the Thames estuary, UK

Boyd A. McKew, Frédéric Coulon, A. Mark Osborn, Kenneth N. Timmis, Terry J. McGenity

Journal:

Environmental Microbiology

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

20

Limits of life in MgCl2-containing environments: chaotropicity defines the window

John E. Hallsworth, Michail M. Yakimov, Peter N. Golyshin, Jenny L. M. Gillion, Giuseppe D'Auria, Flavia De Lima Alves, Violetta La Cono, Maria Genovese, Boyd A. McKew, Sandra L. Hayes, Gayle Harris,

Journal:

Environmental Microbiology

Year:

2007

Language:

english

File:

PDF, 230 KB

english, 2007

21

Efficacy of intervention strategies for bioremediation of crude oil in marine systems and effects on indigenous hydrocarbonoclastic bacteria

Boyd A. McKew, Frédéric Coulon, Michail M. Yakimov, Renata Denaro, Maria Genovese, Cindy J. Smith, A. Mark Osborn, Kenneth N. Timmis, Terry J. McGenity

Journal:

Environmental Microbiology

Year:

2007

Language:

english

File:

PDF, 384 KB

english, 2007

22

Temporal and spatial changes in the microbial bioaerosol communities in green-waste composting

Louise J. Pankhurst, Corinne Whitby, Mark Pawlett, Lee D. Larcombe, Boyd McKew, Lewis J. Deacon, Sarah L. Morgan, Raffaella Villa, Gillian H. Drew, Sean Tyrrel, Simon J.T. Pollard, Frédéric Coulon

Journal:

FEMS Microbiology Ecology

Year:

2012

Language:

english

File:

PDF, 399 KB

english, 2012

23

Resistance and resilience of benthic biofilm communities from a temperate saltmarsh to desiccation and rewetting

McKew, Boyd A, Taylor, Joe D, McGenity, Terry J, Underwood, Graham J C

Journal:

The ISME Journal

Year:

2010

Language:

english

File:

PDF, 783 KB

english, 2010

24

Novel Synthesis and Structural Characterization of a High-Affinity Paramagnetic Kinase Probe for the Identification of Non-ATP Site Binders by Nuclear Magnetic Resonance

Moy, Franklin J., Lee, Arthur, Gavrin, Lori Krim, Xu, Zhang Bao, Sievers, Annette, Kieras, Elizabeth, Stochaj, Wayne, Mosyak, Lidia, McKew, John, Tsao, Désirée H. H.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.57 MB

english, 2010

25

Sa.29. Efficacy of Giripladib, a Novel Inhibitor of Cytosolic Phospholipase A2α, in Two Different Mouse Models of Rheumatoid Arthritis

Jennifer Lamothe, Katherine Lee, Scott Schelling, Nancy Stedman, Michael Leach, John McKew, James Clark, Cheryl Nickerson-Nutter, Martin Hegen

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 72 KB

english, 2008

26

Blockade of cytosolic phospholipase A2α prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses

Suzana Marusic, Paresh Thakker, Jeffrey W. Pelker, Nancy L. Stedman, Katherine L. Lee, John C. McKew, Lixin Han, Xin Xu, Stan F. Wolf, Adam J. Borey, Junqing Cui, Marina W.H. Shen, Fran Donahue, Mina

Journal:

Journal of Neuroimmunology

Year:

2008

Language:

english

File:

PDF, 1.29 MB

english, 2008

27

Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization

McKew, John C., Foley, Megan A., Thakker, Paresh, Behnke, Mark L., Lovering, Frank E., Sum, Fuk-Wah, Tam, Steve, Wu, Kun, Shen, Marina W. H., Zhang, Wen

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 423 KB

english, 2006

28

The cPLA2α inhibitor efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid

Cheryl L. Nickerson-Nutter, Debra Goodwin, Marina W.H. Shen, Christy Damphousse, Weili Duan, Tarek A. Samad, John C. McKew, Katherine L. Lee, Margaret M. Zaleska, Nevena Mollova, James D. Clark

Journal:

Neuropharmacology

Year:

2011

Language:

english

File:

PDF, 572 KB

english, 2011

29

Impact of a simulated oil spill on benthic phototrophs and nitrogen-fixing bacteria in mudflat mesocosms

Panagiota-Myrsini Chronopoulou, Anne Fahy, Frédéric Coulon, Sandrine Païssé, Marisol Goñi-Urriza, Louis Peperzak, Laura Acuña Alvarez, Boyd A. McKew, Tracy Lawson, Kenneth N. Timmis, Robert Duran, Gra

Journal:

Environmental Microbiology

Year:

2012

Language:

english

File:

PDF, 944 KB

english, 2012

30

Central Role of Dynamic Tidal Biofilms Dominated by Aerobic Hydrocarbonoclastic Bacteria and Diatoms in the Biodegradation of Hydrocarbons in Coastal Mudflats

Coulon, F., Chronopoulou, P.-M., Fahy, A., Paisse, S., Goni-Urriza, M., Peperzak, L., Acuna Alvarez, L., McKew, B. A., Brussaard, C. P. D., Underwood, G. J. C., Timmis, K. N., Duran, R., McGenity, T.

Journal:

Applied and Environmental Microbiology

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

31

Plasma and Tissue Concentrations of α-Tocopherol and δ-Tocopherol Following High Dose Dietary Supplementation in Mice

Baxter, Laura L., Marugan, Juan J., Xiao, Jingbo, Incao, Art, McKew, John C., Zheng, Wei, Pavan, William J.

Journal:

Year:

2012

Language:

english

File:

PDF, 381 KB

english, 2012

32

Diversity ofBacillus-like organisms isolated from deep-sea hypersaline anoxic sediments

Andrea M Sass, Boyd A McKew, Henrik Sass, Jörg Fichtel, Kenneth N Timmis, Terry J McGenity

Journal:

Aquatic Biosystems

Year:

2008

Language:

english

File:

PDF, 324 KB

english, 2008

33

Marine crude-oil biodegradation: a central role for interspecies interactions

Terry J McGenity, Benjamin D Folwell, Boyd A McKew, Gbemisola O Sanni

Journal:

Aquatic Biosystems

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

34

Synthesis of Pyrazolo[1,5-α]pyrimidinone Regioisomers

Gavrin, Lori K., Lee, Arthur, Provencher, Brian A., Massefski, Walter W., Huhn, Stephen D., Ciszewski, Gregory M., Cole, Derek C., McKew, John C.

Journal:

Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 105 KB

english, 2007

35

Reactions of Functionalized Sulfonamides: Application to Lowering the Lipophilicity of Cytosolic Phospholipase A 2 α Inhibitors ∥

Chen, Lihren, Wang, Weiheng, Lee, Katherine L., Shen, Marina W. H., Murphy, Elizabeth A., Zhang, Wen, Xu, Xin, Tam, Steve, Nickerson-Nutter, Cheryl, Goodwin, Debra G., Clark, James D., McKew, John C.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

36

A quantitative high throughput assay for identifying gametocytocidal compounds

Tanaka, Takeshi Q., Dehdashti, Seameen J., Nguyen, Dac-Trung, McKew, John C., Zheng, Wei, Williamson, Kim C.

Journal:

Molecular and Biochemical Parasitology

Year:

2013

Language:

english

File:

PDF, 882 KB

english, 2013

37

Plasticity in the proteome of Emiliania huxleyi CCMP 1516 to extremes of light is highly targeted

McKew, Boyd A., Lefebvre, Stephane C., Achterberg, Eric P., Metodieva, Gergana, Raines, Christine A., Metodiev, Metodi V., Geider, Richard J.

Journal:

New Phytologist

Year:

2013

Language:

english

File:

PDF, 2.44 MB

english, 2013

38

Preparation of 4,5-Disubstituted Pyrimidines: Ring Substitution of 5-Mesyloxymethylpyrimidines

Sard, Howard, Gonzalez, Mario D., Mahadevan, Anu, McKew, John

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 48 KB

english, 2000

39

Piperazine Sulfonamides as Potent, Selective, and Orally Available 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors with Efficacy in the Rat Cortisone-Induced Hyperinsulinemia Model

Xiang, Jason, Wan, Zhao-Kui, Li, Huan-Qiu, Ipek, Manus, Binnun, Eva, Nunez, Jill, Chen, Lihren, McKew, John C., Mansour, Tarek S., Xu, Xin, Suri, Vipin, Tam, May, Xing, Yuzhe, Li, Xiangping, Hahm, Seu

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 156 KB

english, 2008

40

New Financial and Research Models for Pediatric Orphan Drug Development: Focus on the NCATS TRND Program

Shen, John, Grewal, Gurmit, Pilon, Andre M., McKew, John C.

Journal:

Pharmaceutical Medicine

Year:

2014

Language:

english

File:

PDF, 231 KB

english, 2014

41

34 Audit of management of neutropenic sepsis in adults receiving systemic anticancer therapy within Belfast Health and Social Care Trust

Mckew, J.R., McCaffrey, S., Merron, B., Gallagher, P., Finnegan, D., Scullin, P., Johnston, R., Hurwitz, J.

Journal:

Year:

2013

Language:

english

File:

PDF, 45 KB

english, 2013

42

Delta-tocopherol facilitates generation of induced pluripotent stem cells from fibroblasts with Niemann-Pick disease type C

Wang, Mengqiao, Yu, Daozhan, Swaroop, Manju, Yang, Rongze, McKew, John C., Gong, Da-Wei, Zheng, Wei

Journal:

Molecular Genetics and Metabolism

Year:

2014

Language:

english

File:

PDF, 46 KB

english, 2014

43

NIH TRND program: successes in preclinical therapeutic development

McKew, John C., Pilon, Andre M.

Journal:

Trends in Pharmacological Sciences

Year:

2013

Language:

english

File:

PDF, 127 KB

english, 2013

44

FRIDAY, SEPT. 3RD.

McKew, John C., Pilon, Andre M.

Journal:

Year:

1897

Language:

english

File:

PDF, 427 KB

english, 1897

45

Why the Middleman?

Charles Mckew Parr

Journal:

Journal of Business of the University of Chicago

Year:

1944

Language:

english

File:

PDF, 396 KB

english, 1944

46

Mutation Update for GNE Gene Variants Associated with GNE Myopathy

Celeste, Frank V., Vilboux, Thierry, Ciccone, Carla, de Dios, John Karl, Malicdan, May Christine V., Leoyklang, Petcharat, McKew, John C., Gahl, William A., Carrillo-Carrasco, Nuria, Huizing, Marjan

Journal:

Year:

2014

Language:

english

File:

PDF, 940 KB

english, 2014

47

Doubly Diastereoselective Iodolactonizations: Olefin and Face Selectivity in Nona-2,7-diene-5-carboxylic Acid Cyclizations

McKew, John C., Olmstead, Marilyn M., Kurth, Mark J.

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 542 KB

english, 1994

48

Indole Cytosolic Phospholipase A 2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1 H -indol-3-yl]propyl}benzoic Acid, Efipladib

McKew, John C., Lee, Katherine L., Shen, Marina W. H., Thakker, Paresh, Foley, Megan A., Behnke, Mark L., Hu, Baihua, Sum, Fuk-Wah, Tam, Steve, Hu, Yonghan, Chen, Lihren, Kirincich, Steven J., Michala

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 782 KB

english, 2008

49

Topical application of the bee hive protectant propolis is well tolerated and improves human diabetic foot ulcer healing in a prospective feasibility study

Henshaw, Frances R., Bolton, Thyra, Nube, Vanessa, Hood, Anita, Veldhoen, Danielle, Pfrunder, Louise, McKew, Genevieve L., Macleod, Colin, McLennan, Susan V., Twigg, Stephen M.

Journal:

Journal of Diabetes and its Complications

Year:

2014

Language:

english

File:

PDF, 545 KB

english, 2014

50

Iterative enolate Claisen rearrangements: versatile route to optically pure 2,7-nonadiene-5-carboxylic acids

McKew, John C., Kurth, Mark J.

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 974 KB

english, 1993

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